|
|
 |
|
|
|
|
|
|
Some 2.500 years ago already, Hippokrates,
the forefather of all medical doctors, successfully treated
pain and
fever with the bitter extract of the willow bark. This extract
contained a large portion of salicylic acid, the prototype of
today's Aspirin®.
Since then, salicylic acid and the later further developed acetylsalicylic
acid has been successfully used in pain therapy.
However, the exact mechanism
of acetylsalicylic acid's action was only discovered some
thirty years ago by Sir John Vane. Acetylsalicylic acid inhibits
the synthesis of endogenous substances, prostaglandins, which
|
can, amongst others, activate and
increase painful states. At the same time it was discovered,
that prostaglandins' synthesis in blood platelets (thrombocytes)
is inhibited by acetylsalicylic acid, by which a conglomeration
of blood platelets (thrombocyte aggregation) is prevented.
With this, the spectrum for application was extended to prophylactic
treatment of heart
attacks and strokes as well as therapy thereof. Here, intake
of the low acetylsalicylic acid dosage Aspirin®
Protect is advised as a preventative measure against re-infarction,
thrombosis and after coronary surgery. More recent studies even
point to a potentially prophylactic
effect in the emergence of cancer. |
| |
|
|
|
| |
|
|
 |
|
|
|
|
|
|
|
Contact
|
Sitemap
|
Deutsch
